NanoSynthons

Defining Elemental Nanoscience

Literature References

Dendrons and Dendrimers

STARBURST® Dendrimers:  Molecular Level Control of Size, Shape, Surface Chemistry, Topology and Flexibility from Atoms to Macroscopic Matter,” D.A. Tomalia, A.M. Naylor W.A. Goddard III, Angew. Chem. Int. Ed. Engl., 29(2), 138-75 (1990).

Dendrimers and Other Dendritic Polymers,” edited by D.A. Tomalia and J.M.J. Fréchet, J. Wiley & Sons Ltd., Chichester (2001).

“Birth of a New Macromolecular Architecture:  Dendrimers as Quantized Building Blocks for Nanoscale Synthetic Organic Chemistry, D.A. Tomalia, Aldrichimica Acta, 37(2) 39-57 (2004). PDF

“The Dendritic State,” D.A. Tomalia, Materials Today, pp. 34-46, March 2005.

Birth of a New Macromolecular Architecture:  Dendrimers as Quantized Building Blocks for Nanoscale Synthetic Polymer Chemistry,” D.A. Tomalia, Prog. Polym. Sci., 30, 294-324 (2005). 

“Poly(amidoamine) Dendrimers,” D.A. Tomalia and L.S. Nixon in Polymer Data Handbook, Second edition, (James E. Mark, editor), Oxford University Press, New York, 356-362 (2009).

"Dendrimers, Dendrons and Dendritic Polymers," D.A. Tomalia, Jorn B. Christensen, and Ulrik Boas. Cambridge University Press, (2012)

Dendritic effects: dependency of dendritic nano-periodic property patterns on critical nanoscale design parameters (CNDPs)” D.A. Tomalia, New J. Chem.,2012,36,264-281

"Twenty-First Century Polymer Science After Staudinger: The Emergence of Dendrimers/Dendritic Polymers as a Fourth Major Architecture and  Window to a New Nano-periodic System", Donald A. Tomalia in Hierarchical Macromolecular Structures: 60 Years after the Staudinger Nobel Prize I, 321-389 (2013)

Dendrimer-Based Nanomedicine

Poly(amidoamine) (PAMAM) Dendrimers:  From Biomimicry to Drug Delivery and Biomedical Applications,” R. Esfand, D.A. Tomalia, Drug Discovery Today, 6(8), 427-436 (2001).

Designed Dendrimer Syntheses By Self-Assembly of Single Site, ssDNA Functionalized Dendrons,” C.R. DeMattei, B. Huang, D.A. Tomalia, NanoLetters, 4(5), 771-777 (2004).

“Dendrimers as Multi-Purpose Nanodevices for Oncology Drug Delivery and Diagnostic Imaging,” D.A. Tomalia, L.A. Reyna, S. Svenson, Biochemical Society Transactions, 35(1), 61-67, 2007 PDF

Dendrimer-Based Drug and Imaging Conjugates:  Design Considerations for Nanomedical Applications,” R.M. Kannan, A.R. Menjoge, D.A. Tomalia, Drug Discovery Today, 15, 5/6, 171-185 (2010).

"An Architectural Journey: From Trees, Dendrons/Dendrimers to Nanomedicine"  H. Stanwix, D.A. Tomalia, Nanomedicine, 7(7), 953-956 (2012) PDF

“A Novel RNA Oligonucleotide Improves Liver Function and Inhibits Liver Carcinogenesis In Vivo,” V. Reebye, P. Saetrom, P.J. Mintz, K.W. Huang, P. Swiderski, L. Peng, C. Liu, X.X. Liu, S. Jensen, D. Zacharoulis, N. Kostomitsopoulos, N. Kasahara, J.P. Nicholls, L.R. Jiao, M. Pai, M. Mizandari, T. Chikovani, M.M. Emara, A. Haoudi, D.A. Tomalia, J.J. Rossi, N.A. Habib, D.R. Spalding, Hepatology, doi:  10.1002/hep.26669.

Emerging concepts in dendrimer-based nanomedicine: from design principles to clinical applications” Kannan RM, Nance E, Kannan S, Tomalia D, J Intern Med 2014; doi: 10.1111/joim.12280.

Dendrons/Dendrimers:  A Window to a New Nano-Periodic System

“In Quest of a Systematic Framework for Unifying and Defining Synthetic Nanoscience,” D.A. Tomalia, J. of Nanoparticle Research, 11, 1251-1310 (2009). PDF

Dendrons/Dendrimers":  Quantized Nano-element Like Building Blocks for Soft-Soft and Soft-Hard Nano-compound Synthesis,” D.A. Tomalia, Soft Matter, 6, 456-474 (2010).

“Dendrimers as Quantized Nano-modules in the Nanotechnology Field,” J.B. Christensen, D.A. Tomalia, in Chapter 1; Designing Dendrimers (eds., S. Campagna, P. Ceroni, F. Puntoriero), J.Wiley & Sons, Hoboken, NJ, pp. 1-33 (2012).

"Proposed Taxonomy and Classification Strategy for Well-Defined, Soft Matter Nanoscale Building Blocks”, J.B. Christensen and D.A. Tomalia in Organic Nanomaterials: Syntheses, Characterization, and Device Applications (eds. T. Torres, G. Bottari), J.Wiley, (2013).

Regio-specific Size, Shape and Surface Chemistry Designed Dendrimers Based on Differentiated Dendroid Templates,”  S. Tang, D.A. Tomalia, B.G. Orr, J.R. Baker Jr., B. Huang, New J. Chem., 37(3) 690-700 (2013).

"IN QUEST OF A SYSTEMATIC FRAMEWORK FOR UNIFYING AND DEFINING NANOSCIENCE"
DONALD A. TOMALIA and SHIV N. KHANNA, Mod. Phys. Lett. B 28, 1430002 (2014) [48 pages] DOI: 10.1142/S0217984914300026